Retroviral Expression in Embryonic Stem Cells and Hematopoietic Stem Cells
نویسندگان
چکیده
منابع مشابه
Retroviral expression in embryonic stem cells and hematopoietic stem cells.
Achieving long-term retroviral expression in primary cells has been problematic. De novo DNA methylation of infecting proviruses has been proposed as a major cause of this transcriptional repression. Here we report the development of a mouse stem cell virus (MSCV) long terminal repeat-based retroviral vector that is expressed in both embryonic stem (ES) cells and hematopoietic stem (HS) cells. ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2000
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.20.20.7419-7426.2000